Results from the SOFT Suppression of Ovarian Function Trial study published in suggest that premenopausal women diagnosed with hormone-receptor-positive breast cancer can be successfully treated with the aromatase inhibitor Aromasin if their ovarian function is suppressed. You should not take an aromatase inhibitor if you are breastfeeding, pregnant, trying to get pregnant, or if there is any chance that you could be pregnant.
Aromatase inhibitors may cause damage to developing embryos. You should use an effective non-hormonal type of birth control — such as condoms, a diaphragm along with spermicide, or a non-hormonal I.
Ask your doctor which type of non-hormonal birth control would be best for you, as well as how long you should use this type of birth control after you stop taking an aromatase inhibitor. A number of studies have compared aromatase inhibitors with tamoxifen to see which type of medicine was more effective in treating early-stage, hormone-receptor-positive breast cancer in postmenopausal women. Based on the results, most doctors recommend that after initial treatment surgery and possibly chemotherapy and radiation therapy :.
Aromatase inhibitors tend to cause fewer serious side effects than tamoxifen, such as blood clots, stroke, and endometrial cancer. But aromatase inhibitors can cause more heart problems , more bone loss osteoporosis , and more broken bones than tamoxifen, at least for the first few years of treatment.
If you and your doctor are considering an aromatase inhibitor as part of your treatment plan, you may want to ask your doctor about having a bone density test to see if a bone strengthening medicine might be necessary while you're taking the aromatase inhibitor.
The most common side effects of aromatase inhibitors are joint stiffness or joint pain. Each patient completed a patient preference form. There was no significant change in FACT-B-ES overall scores or ES scores while patients were taking anastrozole or letrozole and no significant differences between drugs. No differences in frequency, grade, or range of side effects were seen between drugs. Of patients, 49 I sort of had achy bones, achy limbs as well, which caused me a bit of concern at one point.
Which I had some tests done but everything was absolutely fine. And then the Arimidex I think has been better for me personally. And again that can be a side effect, but I think mine has been a combination of both. So it would be interesting to see if I come off the Arimidex if it, how I would feel after that. Next week. How would you feel about coming off the Arimidex?
Because about a couple of years ago I thought, when I thought I was going to be taken off it, I was still unsure because it was my safety net. And if anything was going to go wrong, it was going to go wrong before now. And I hope that perhaps I might lose a little bit of weight. Or I might not see any difference at all. I had tamoxifen for two years. Then I was told the newest thing is that now you go from tamoxifen to Arimidex. Which I did. So I went onto Aromasin.
But I had side effects from all of those. I had the most ridiculous things, carpal tunnel syndrome, which people think is repetitive strain injury. And I stopped working. And then discovered that was a side effect of one of the drugs I was on. And had injections and that cleared up. But that was my choice. Do you know which side effects came with which of the drugs at all or…. Well I know that the blindness came with the tamoxifen, and I know the skin lesions came with tamoxifen. But thank goodness for Roche Posay.
I just slap on two or three times a day, the products, and that sort of calms my skin down. And you mentioned that you were taking tamoxifen for two years? Now I think Aromasin produced Carpal Tunnel syndrome. And I think it was the, no sorry, Arimidex produced Carpal Tunnel syndrome. It could have been Aromasin or it could have been Arimidex that produced the heart problems.
But I think it had a whole list of cancer drugs that could cause heart problems. So it could have been either. And how long did you take the Arimidex for before going onto the Aromasin?
I think Arimidex I was on for two years, and then Aromasin for one year. They keep you on hormonal drugs for about five years. And then they reckon that everything should be zapped by then. Although I know with certain cancers, some people can stay on Tamoxifen, oh forever.
But it depends on the type of cancer you have And are you taking Aromasin at the moment? You mentioned that you had some of your care in the UK, which was private health care. And some in France. And you have mentioned before that you had some in Germany. Can you go through and tell me which care you had where? And how it differed? So I rang him up and described the problems.
It was like Star Wars. He gave me, my eyes still water a bit, and he gave me marvellous drops which soothe them, calm them down.
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